Regular Article PLATELETS AND THROMBOPOIESIS Interaction of platelet-derived autotaxin with tumor integrin aVb3 controls metastasis of breast cancer cells to bone
نویسندگان
چکیده
Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche 1033, Université Claude Bernard Lyon 1, Faculté de Médecine Lyon Est, Lyon, France; Department of Physiology, University of Tennessee Health Science Center, Memphis, TN; Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche 1037, Université de Toulouse III, Institut Claudius Regaud, Toulouse, France; EA4174, Université Claude Bernard Lyon 1, Faculté de Médecine Lyon Est, Lyon, France; and Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN
منابع مشابه
Regular Article PLATELETS AND THROMBOPOIESIS A novel and essential role for FcgRIIa in cancer cell–induced platelet activation
There is increasing evidence supporting an association between cancer growth, metastasis, and platelet secretion. An association between thrombocytosis and cancer death was first reported in 1872 by Reiss and colleagues and brought to our attention again in 1964. Boneu et al, in 1984, first reported the presence of degranulated platelets, characterized by low levels of adenosine 59-diphosphate ...
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An association between platelets, angiogenesis, and cancer has long been recognized, but the mechanisms linking them remains unclear. Platelets regulate new blood vessel growth through numerous stimulators and inhibitors of angiogenesis by several pathways, including differential exocytosis of angiogenesis regulators. Herein, we investigated the differential release of angiogenesis stimulators ...
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1Department of Molecular Cardiology, Joseph J. Jacobs Center for Thrombosis and Vascular Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH; 2First Affiliated Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi, China; 3Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY; and 4Taussig Cancer...
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